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KMID : 0043319940170010031
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Archives of Pharmacal Research
1994 Volume.17 No. 1 p.31 ~ p.35
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Antiinflammatory Activity of Isoflavonoids from Pueraria Radix and Biochanin A Derivatives
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Lee Song-Jin
Baek Ho-Jin
Lee Chang-Hee
Kim Hyun-Pyo
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Abstract
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For comparing with flavones/flavonols, isoflavonoids isolated from Pueraria radix and chemically synthesized from biochanin A were evaluated for the antiinflammatory activity using mouse ear edema test, Isoflavonoids such as daildzein and puerarin hsowed the significant antiinflammatory activity at a dose of 2 mg/mouse, although their activity was generally less than that of flavones/flavonols. 7-O-Substitution of biochanin A was not facorable for the antiinflammatory activity.
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KEYWORD
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Antiinflammation, Isoflavonoid, Pueraria radix, Biochanin A
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